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== Research == |
== Research == |
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Mooreβs research focuses on the development and application of informatics methods for identifying combinations of DNA sequence variations and environmental factors that are predictive of human health and [[Genetic_disorder#Multifactorial_and_polygenic_.28complex.29_disorders|complex disease]]. For example, he developed the [[multifactor dimensionality reduction]] (MDR) |
Mooreβs research focuses on the development and application of [[artificial intelligence]] and [[machine learning]] methods for modeling complex patterns in biomedical [[big data]]. A central focus is using informatics methods for identifying combinations of DNA sequence variations and environmental factors that are predictive of human health and [[Genetic_disorder#Multifactorial_and_polygenic_.28complex.29_disorders|complex disease]]. For example, he developed the [[multifactor dimensionality reduction]] (MDR) machine learning method for detecting and characterizing combinations of attributes or independent variables that interact to influence a dependent or class variable. He then applied MDR for improved understanding of the interplay of multiple genetic polymorphisms of [[Quantitative trait locus|complex traits]] in [[Genome-wide association study|genome-wide association studies]]. |
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He is a former member of the [[United States National Library of Medicine|National Library of Medicine]] grant review committee (BLIRC). He is the founding Editor-in-Chief of the journal ''BioData Mining'',<ref>[http://www.biodatamining.org/about/edboard BioData Mining Journal]</ref> He has published more than |
He is a former member of the [[United States National Library of Medicine|National Library of Medicine]] grant review committee (BLIRC). He is the founding Editor-in-Chief of the journal ''BioData Mining'',<ref>[http://www.biodatamining.org/about/edboard BioData Mining Journal]</ref> He has published more than 450 peer reviewed articles, book chapters and editorials. His translational bioinformatics research program has been continuously funded by multiple grants from the [[National Institutes of Health]] for more than 15 years. |
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== Honors == |
== Honors == |
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In 2011 he was elected as a Fellow of the [[American Association for the Advancement of Science]] (AAAS) and was selected as a Kavli Fellow of the National Academy of Sciences in 2013. In 2015 he was elected a Fellow of the [[American College of Medical Informatics]] (ACMI). |
In 2011 he was elected as a Fellow of the [[American Association for the Advancement of Science]] (AAAS) and was selected as a Kavli Fellow of the [[National Academy of Sciences]] in 2013. In 2015 he was elected a Fellow of the [[American College of Medical Informatics]] (ACMI). |
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==Publications== |
==Publications== |
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