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| notable_students = Brett McKinney<ref>[http://insilico.utulsa.edu/ McKinney Lab]</ref> |
| notable_students = Brett McKinney<ref>[http://insilico.utulsa.edu/ McKinney Lab]</ref> |
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| known_for = [[Multifactor dimensionality reduction]]<BR>Founding Director of the |
| known_for = [[Multifactor dimensionality reduction]]<BR>Founding Director of the Institute for Quantitative Biomedical Sciences (iQBS) at Dartmouth College<ref>[http://iqbs.org/]</ref> |
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| prizes = [[Fellow of the AAAS]]<ref>[http://www.aaas.org/news/releases/2011/1206fellows.shtml Jason H. Moore, Fellow of the AAAS]</ref> |
| prizes = [[Fellow of the AAAS]]<ref>[http://www.aaas.org/news/releases/2011/1206fellows.shtml Jason H. Moore, Fellow of the AAAS]</ref> |
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}} |
}} |
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'''Jason H. Moore, PhD''', is a translational bioinformatics scientist and [[Human genetics|human geneticist]]. Dr. Moore’s research focuses on |
'''Jason H. Moore, PhD''', is a translational bioinformatics scientist and [[Human genetics|human geneticist]]. Dr. Moore’s research focuses on the development and application of informatics methods for identifying combinations of DNA sequence variations and environmental factors that are predictive of human health and [[Genetic_disorder#Multifactorial_and_polygenic_.28complex.29_disorders|complex disease]]. Along the way, he pioneered the theory and formalisms of the [[multifactor dimensionality reduction]] (MDR) [[machine learning]] method for detecting and characterizing combinations of attributes or independent variables that interact to influence a dependent or class variable. He then applied MDR for improved understanding of the interplay of multiple genetic polymorphisms of [[Quantitative trait locus|complex traits]] in [[Genome-wide association study|genome-wide association studies]]. Of note, his seminal MDR work has been cited > 900 times and this led the scientific community to publish over 300 manuscripts in the nascent MDR field. He is a standing member of the [[United States National Library of Medicine|National Library of Medicine]] grant review committee (BLIRC). He is the founding Editor-in-Chief of the journal BioData Mining,<ref>[http://www.biodatamining.org/about/edboard BioData Mining Journal]</ref> and the Founder and Director of the Institute for Quantitative Biomedical Sciences at [[Geisel School of Medicine]] of [[Dartmouth College]] where he also serves as Associate Director for Bioinformatics of the [[Norris Cotton Cancer Center]]. Dr. Moore has mentored more than 32 graduate and postgraduate students and has published more than 300 peer reviewed articles, book chapters and editorials. His translational bioinformatics research program has been continuously funded by multiple grants from the [[National Institutes of Health]] for the last 12 years. He was recognized by his peers for his contributions to translational bioinformatics and human genetics through election as a Fellow of the [[American Association for the Advancement of Science]] (AAAS) in 2011. |
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Currently, Dr. Moore is Founder and Director of the Institute for Quantitative Biomedical Sciences at [[Geisel School of Medicine]] of [[Dartmouth College]]. |
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Medical School and Dartmouth College at [[Columbia University]]. Dr. Moore mentored 11 graduate students and faculty members and has published over 200 peer reviewed articles. |
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==Publications== |
==Publications== |
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==External links== |
==External links== |
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* [http://geiselmed.dartmouth.edu/faculty/facultydb/view.php?uid=2882 Jason H Moore at Dartmouth] |
* [http://geiselmed.dartmouth.edu/faculty/facultydb/view.php?uid=2882 Jason H. Moore's faculty profile at Dartmouth College] |
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* [http://www.epistasis.org Jason H. Moore's research laboratory at Dartmouth College] |
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